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Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine
617-732-2528
Publications View
Tandem SH2 domains confer high specificity in tyrosine kinase signaling.
Authors: Authors: Ottinger EA, Botfield MC, Shoelson SE.
J Biol Chem
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The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.
Authors: Authors: Lupher ML, Songyang Z, Shoelson SE, Cantley LC, Band H.
J Biol Chem
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SH2 and PTB domain interactions in tyrosine kinase signal transduction.
Authors: Authors: Shoelson SE.
Curr Opin Chem Biol
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Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.
Authors: Authors: Rapoport I, Miyazaki M, Boll W, Duckworth B, Cantley LC, Shoelson S, Kirchhausen T.
EMBO J
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Conformational changes of the insulin receptor upon insulin binding and activation as monitored by fluorescence spectroscopy.
Authors: Authors: Lee J, Pilch PF, Shoelson SE, Scarlata SF.
Biochemistry
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Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking.
Authors: Authors: Giorgetti-Peraldi S, Ottinger E, Wolf G, Ye B, Burke TR, Shoelson SE.
Mol Cell Biol
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Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.
Authors: Authors: Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE.
J Biol Chem
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The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling.
Authors: Authors: Trüb T, Frantz JD, Miyazaki M, Band H, Shoelson SE.
J Biol Chem
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Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling.
Authors: Authors: Ricketts WA, Rose DW, Shoelson S, Olefsky JM.
J Biol Chem
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Tyrosine-phosphorylated Cbl binds to Crk after T cell activation.
Authors: Authors: Sawasdikosol S, Chang JH, Pratt JC, Wolf G, Shoelson SE, Burakoff SJ.
J Immunol
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