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Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine
617-732-2528
Publications View
Prevention of fat-induced insulin resistance by salicylate.
Authors: Authors: Kim JK, Kim YJ, Fillmore JJ, Chen Y, Moore I, Lee J, Yuan M, Li ZW, Karin M, Perret P, Shoelson SE, Shulman GI.
J Clin Invest
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Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis.
Authors: Authors: Lindholm CK, Frantz JD, Shoelson SE, Welsh M.
Biochem Biophys Res Commun
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Crystal structure of human frataxin.
Authors: Authors: Dhe-Paganon S, Shigeta R, Chi YI, Ristow M, Shoelson SE.
J Biol Chem
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Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps.
Authors: Authors: O'Reilly AM, Pluskey S, Shoelson SE, Neel BG.
Mol Cell Biol
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Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Authors: Authors: Dhe-Paganon S, Ottinger EA, Nolte RT, Eck MJ, Shoelson SE.
Proc Natl Acad Sci U S A
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Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site.
Authors: Authors: Rapoport I, Chen YC, Cupers P, Shoelson SE, Kirchhausen T.
EMBO J
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Identification of SOCS-3 as a potential mediator of central leptin resistance.
Authors: Authors: Bjørbaek C, Elmquist JK, Frantz JD, Shoelson SE, Flier JS.
Mol Cell
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Crystal structure of the tyrosine phosphatase SHP-2.
Authors: Authors: Hof P, Pluskey S, Dhe-Paganon S, Eck MJ, Shoelson SE.
Cell
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Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins.
Authors: Authors: Welsh M, Songyang Z, Frantz JD, Trüb T, Reedquist KA, Karlsson T, Miyazaki M, Cantley LC, Band H, Shoelson SE.
Oncogene
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Correlation between binding and dynamics at SH2 domain interfaces.
Authors: Authors: Kay LE, Muhandiram DR, Wolf G, Shoelson SE, Forman-Kay JD.
Nat Struct Biol
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