Steven E. Shoelson

Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine

617-732-2528

Publications

Publications View

Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide.

Authors: Authors: Domchek SM, Auger KR, Chatterjee S, Burke TR, Shoelson SE.
Biochemistry 1992-10-20
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Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

Authors: Authors: Backer JM, Myers MG, Shoelson SE, Chin DJ, Sun XJ, Miralpeix M, Hu P, Margolis B, Skolnik EY, Schlessinger J, et al.
EMBO J 1992-09-01
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The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.

Authors: Authors: Backer JM, Shoelson SE, Weiss MA, Hua QX, Cheatham RB, Haring E, Cahill DC, White MF.
J Cell Biol 1992-08-01
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Substitution of the insulin receptor transmembrane domain with the c-neu/erbB2 transmembrane domain constitutively activates the insulin receptor kinase in vitro.

Authors: Authors: Yamada K, Goncalves E, Kahn CR, Shoelson SE.
J Biol Chem 1992-06-25
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Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro.

Authors: Authors: Auger KR, Carpenter CL, Shoelson SE, Piwnica-Worms H, Cantley LC.
J Biol Chem 1992-03-15
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YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase.

Authors: Authors: Shoelson SE, Chatterjee S, Chaudhuri M, White MF.
Proc Natl Acad Sci U S A 1992-03-15
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Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions.

Authors: Authors: Shoelson SE, Lu ZX, Parlautan L, Lynch CS, Weiss MA.
Biochemistry 1992-02-18
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Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region.

Authors: Authors: Backer JM, Shoelson SE, Haring E, White MF.
J Cell Biol 1991-12-01
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Receptor binding redefined by a structural switch in a mutant human insulin.

Authors: Authors: Hua QX, Shoelson SE, Kochoyan M, Weiss MA.
Nature 1991-11-21
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Autophosphorylation within insulin receptor beta-subunits can occur as an intramolecular process.

Authors: Authors: Shoelson SE, Boni-Schnetzler M, Pilch PF, Kahn CR.
Biochemistry 1991-08-06
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