Steven E. Shoelson

Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine

617-732-2528

Publications

Publications View

Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design.

Authors: Authors: Weiss MA, Hua QX, Lynch CS, Frank BH, Shoelson SE.
Biochemistry 1991-07-30
View full abstract on Pubmed

NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition.

Authors: Authors: Weiss MA, Frank BH, Khait I, Pekar A, Heiney R, Shoelson SE, Neuringer LJ.
Biochemistry 1990-09-11
View full abstract on Pubmed

Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics.

Authors: Authors: Weiss MA, Nguyen DT, Khait I, Inouye K, Frank BH, Beckage M, O'Shea E, Shoelson SE, Karplus M, Neuringer LJ.
Biochemistry 1989-12-12
View full abstract on Pubmed

Nonphosphorylatable substrate analogs selectively block autophosphorylation and activation of the insulin receptor, epidermal growth factor receptor, and pp60v-src kinases.

Authors: Authors: Shoelson SE, White MF, Kahn CR.
J Biol Chem 1989-05-15
View full abstract on Pubmed

Lipocortins 1 and 2 as substrates for the insulin receptor kinase in rat liver.

Authors: Authors: Karasik A, Pepinsky RB, Shoelson SE, Kahn CR.
J Biol Chem 1988-08-25
View full abstract on Pubmed

Tryptic activation of the insulin receptor. Proteolytic truncation of the alpha-subunit releases the beta-subunit from inhibitory control.

Authors: Authors: Shoelson SE, White MF, Kahn CR.
J Biol Chem 1988-04-05
View full abstract on Pubmed

A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.

Authors: Authors: White MF, Shoelson SE, Keutmann H, Kahn CR.
J Biol Chem 1988-02-25
View full abstract on Pubmed

High-performance liquid chromatography (HPLC): a rapid, flexible and sensitive method for separating islet proinsulin and insulin.

Authors: Authors: Halban PA, Rhodes CJ, Shoelson SE.
Diabetologia 1986-12-01
View full abstract on Pubmed

Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes.

Authors: Authors: Shoelson SE, Marshall S, Horikoshi H, Kolterman OG, Rubenstein AH, Olefsky JM.
J Clin Endocrinol Metab 1986-07-01
View full abstract on Pubmed

Circulating forms of somatostatinlike immunoreactivity in human plasma.

Authors: Authors: Shoelson SE, Polonsky KS, Nakabayashi T, Jaspan JB, Tager HS.
Am J Physiol 1986-04-01
View full abstract on Pubmed