Steven E. Shoelson

Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine

617-732-2528

Publications

Publications View

Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.

Authors: Authors: Birge RB, Fajardo JE, Reichman C, Shoelson SE, Songyang Z, Cantley LC, Hanafusa H.
Mol Cell Biol 1993-08-01
View full abstract on Pubmed

Optimizing transmembrane domain helicity accelerates insulin receptor internalization and lateral mobility.

Authors: Authors: Goncalves E, Yamada K, Thatte HS, Backer JM, Golan DE, Kahn CR, Shoelson SE.
Proc Natl Acad Sci U S A 1993-06-15
View full abstract on Pubmed

Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance.

Authors: Authors: Payne G, Shoelson SE, Gish GD, Pawson T, Walsh CT.
Proc Natl Acad Sci U S A 1993-06-01
View full abstract on Pubmed

Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit.

Authors: Authors: Carpenter CL, Auger KR, Chanudhuri M, Yoakim M, Schaffhausen B, Shoelson S, Cantley LC.
J Biol Chem 1993-05-05
View full abstract on Pubmed

Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells.

Authors: Authors: Backer JM, Myers MG, Sun XJ, Chin DJ, Shoelson SE, Miralpeix M, White MF.
J Biol Chem 1993-04-15
View full abstract on Pubmed

Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding.

Authors: Authors: Piccione E, Case RD, Domchek SM, Hu P, Chaudhuri M, Backer JM, Schlessinger J, Shoelson SE.
Biochemistry 1993-04-06
View full abstract on Pubmed

A photoaffinity scan maps regions of the p85 SH2 domain involved in phosphoprotein binding.

Authors: Authors: Williams KP, Shoelson SE.
J Biol Chem 1993-03-15
View full abstract on Pubmed

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.

Authors: Authors: Waksman G, Shoelson SE, Pant N, Cowburn D, Kuriyan J.
Cell 1993-03-12
View full abstract on Pubmed

SH2 domains recognize specific phosphopeptide sequences.

Authors: Authors: Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al.
Cell 1993-03-12
View full abstract on Pubmed

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.

Authors: Authors: Eck MJ, Shoelson SE, Harrison SC.
Nature 1993-03-04
View full abstract on Pubmed