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Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine
617-732-2528
Publications View
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.
Authors: Authors: Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al.
Mol Cell Biol
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T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif.
Authors: Authors: Prasad KV, Cai YC, Raab M, Duckworth B, Cantley L, Shoelson SE, Rudd CE.
Proc Natl Acad Sci U S A
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Phosphorylation of synthetic peptides containing Tyr-Met-X-Met motifs by nonreceptor tyrosine kinases in vitro.
Authors: Authors: Garcia P, Shoelson SE, George ST, Hinds DA, Goldberg AR, Miller WT.
J Biol Chem
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Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase.
Authors: Authors: Chuang LM, Myers MG, Backer JM, Shoelson SE, White MF, Birnbaum MJ, Kahn CR.
Mol Cell Biol
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Cooperative self-assembly of SH2 domain fragments restores phosphopeptide binding.
Authors: Authors: Williams KP, Shoelson SE.
Biochemistry
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Expression, purification, and characterization of SH2-containing protein tyrosine phosphatase, SH-PTP2.
Authors: Authors: Sugimoto S, Lechleider RJ, Shoelson SE, Neel BG, Walsh CT.
J Biol Chem
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Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.
Authors: Authors: Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG.
J Biol Chem
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Identification of residues in the beta platelet-derived growth factor receptor that confer specificity for binding to phospholipase C-gamma 1.
Authors: Authors: Larose L, Gish G, Shoelson S, Pawson T.
Oncogene
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Characterization of insulin autoantibodies in relatives of patients with type I diabetes.
Authors: Authors: Castaño L, Ziegler AG, Ziegler R, Shoelson S, Eisenbarth GS.
Diabetes
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Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.
Authors: Authors: Birge RB, Fajardo JE, Reichman C, Shoelson SE, Songyang Z, Cantley LC, Hanafusa H.
Mol Cell Biol
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