Dominic M. Walsh

Dominic M. Walsh, Ph.D.

Lecturer on Neurology

617-525-5059

Publications

Publications View

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease.

Authors: Authors: Wong HK, Veremeyko T, Patel N, Lemere CA, Walsh DM, Esau C, Vanderburg C, Krichevsky AM.
Hum Mol Genet 2013-08-01
View full abstract on Pubmed

Alzheimer brain-derived amyloid ß-protein impairs synaptic remodeling and memory consolidation.

Authors: Authors: Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM.
Neurobiol Aging 2013-05-01
View full abstract on Pubmed

New ELISAs with high specificity for soluble oligomers of amyloid ß-protein detect natural Aß oligomers in human brain but not CSF.

Authors: Authors: Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ.
Alzheimers Dement 2013-03-01
View full abstract on Pubmed

Simple photosystem II water oxidation centre analogues in visible light oxygen and H+ generation.

Authors: Authors: Kim YY, Williams D, Meldrum FC, Walsh D.
Small 2013-01-14
View full abstract on Pubmed

The ELISA-measured increase in cerebrospinal fluid tau that discriminates Alzheimer's disease from other neurodegenerative disorders is not attributable to differential recognition of tau assembly forms.

Authors: Authors: O'Dowd ST, Ardah MT, Johansson P, Lomakin A, Benedek GB, Roberts KA, Cummins G, El Agnaf OM, Svensson J, Zetterberg H, Lynch T, Walsh DM.
J Alzheimers Dis 2013-01-01
View full abstract on Pubmed

Amyloid-ß nanotubes are associated with prion protein-dependent synaptotoxicity.

Authors: Authors: Nicoll AJ, Panico S, Freir DB, Wright D, Terry C, Risse E, Herron CE, O'Malley T, Wadsworth JD, Farrow MA, Walsh DM, Saibil HR, Collinge J.
Nat Commun 2013-01-01
View full abstract on Pubmed

Role of aromatic side chains in amyloid ß-protein aggregation.

Authors: Authors: Cukalevski R, Boland B, Frohm B, Thulin E, Walsh D, Linse S.
ACS Chem Neurosci 2012-12-19
View full abstract on Pubmed

APP mutations in the Aß coding region are associated with abundant cerebral deposition of Aß38.

Authors: Authors: Moro ML, Giaccone G, Lombardi R, Indaco A, Uggetti A, Morbin M, Saccucci S, Di Fede G, Catania M, Walsh DM, Demarchi A, Rozemuller A, Bogdanovic N, Bugiani O, Ghetti B, Tagliavini F.
Acta Neuropathol 2012-12-01
View full abstract on Pubmed

The levels of water-soluble and triton-soluble Aß are increased in Alzheimer's disease brain.

Authors: Authors: McDonald JM, Cairns NJ, Taylor-Reinwald L, Holtzman D, Walsh DM.
Brain Res 2012-04-23
View full abstract on Pubmed

ß-Amyloid carrying the Dutch mutation has diverse effects on calpain-mediated toxicity in hippocampal neurons.

Authors: Authors: Nicholson AM, Wold LA, Walsh DM, Ferreira A.
Mol Med 2012-03-27
View full abstract on Pubmed