Publications View
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
Authors: Authors: Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.
Nat Med
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Nat Med
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Substrate-targeting gamma-secretase modulators.
Authors: Authors: Kukar TL, Ladd TB, Bann MA, Fraering PC, Narlawar R, Maharvi GM, Healy B, Chapman R, Welzel AT, Price RW, Moore B, Rangachari V, Cusack B, Eriksen J, Jansen-West K, Verbeeck C, Yager D, Eckman C, Ye W, Sagi S, Cottrell BA, Torpey J, Rosenberry TL, Fauq A, Wolfe MS, Schmidt B, Walsh DM, Koo EH, Golde TE.
Nature
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Nature
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Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.
Authors: Authors: Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ.
J Neurosci
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J Neurosci
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Exercise and manual auricular acupuncture: a pilot assessor-blind randomised controlled trial. (The acupuncture and personalised exercise programme (APEP) trial).
Authors: Authors: McDonough SM, Liddle SD, Hunter R, Walsh DM, Glasgow P, Gormley G, Hurley D, Delitto A, Park J, Bradbury I, Baxter GD.
BMC Musculoskelet Disord
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BMC Musculoskelet Disord
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Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases.
Authors: Authors: Irvine GB, El-Agnaf OM, Shankar GM, Walsh DM.
Mol Med
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Mol Med
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Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.
Authors: Authors: Farris W, Schütz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ.
Am J Pathol
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Am J Pathol
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A beta oligomers - a decade of discovery.
The APP family of proteins: similarities and differences.
Authors: Authors: Walsh DM, Minogue AM, Sala Frigerio C, Fadeeva JV, Wasco W, Selkoe DJ.
Biochem Soc Trans
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Biochem Soc Trans
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Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.
Authors: Authors: Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL.
J Neurosci
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J Neurosci
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Rapid assessment of severe cognitive impairment in individuals with developmental disabilities.
Authors: Authors: Walsh DM, Finwall J, Touchette PE, McGregor MR, Fernandez GE, Lott IT, Sandman CA.
J Intellect Disabil Res
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J Intellect Disabil Res
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