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Dominic M. Walsh, Ph.D.

Lecturer on Neurology
617-525-5059
Publications View
Patient-derived tau and amyloid-ß facilitate long-term depression in vivo: role of tumour necrosis factor-a and the integrated stress response.
Authors: Authors: Hu NW, Ondrejcak T, Klyubin I, Yang Y, Walsh DM, Livesey FJ, Rowan MJ.
Brain Commun
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Tau and Amyloid ß Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation in Vivo.
Authors: Authors: Ondrejcak T, Klyubin I, Hu NW, O'Malley TT, Corbett GT, Winters R, Perkinton MS, Billinton A, Prenderville JA, Walsh DM, Rowan MJ.
J Neurosci
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Learnings about Aß from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics.
Authors: Authors: Wang Z, Jin M, Hong W, Liu W, Reczek D, Lagomarsino VN, Hu Y, Weeden T, Frosch MP, Young-Pearse TL, Pradier L, Selkoe D, Walsh DM.
Acta Neuropathol Commun
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Methods for the isolation and analysis of Aß from postmortem brain.
Authors: Authors: Hong W, Liu W, Desousa AO, Young-Pearse T, Walsh DM.
Front Neurosci
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Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aß oligomer profiles unaltered by ablation of cellular prion protein.
Authors: Authors: Purro SA, Farmer M, Noble E, Sarell CJ, Powell M, Yip D, Giggins L, Zakka L, Thomas DX, Farrow M, Nicoll AJ, Walsh D, Collinge J.
PLoS One
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NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression.
Authors: Authors: Mengel D, Mok TH, Nihat A, Liu W, Rissman RA, Galasko D, Zetterberg H, Mead S, Collinge J, Walsh DM.
Cells
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Laboratory evolution of a sortase enzyme that modifies amyloid-ß protein.
Authors: Authors: Podracky CJ, An C, DeSousa A, Dorr BM, Walsh DM, Liu DR.
Nat Chem Biol
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Longitudinal plasma p-tau217 is increased in early stages of Alzheimer's disease.
Authors: Authors: Mattsson-Carlgren N, Janelidze S, Palmqvist S, Cullen N, Svenningsson AL, Strandberg O, Mengel D, Walsh DM, Stomrud E, Dage JL, Hansson O.
Brain
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Plasma NT1 Tau is a Specific and Early Marker of Alzheimer's Disease.
Authors: Authors: Mengel D, Janelidze S, Glynn RJ, Liu W, Hansson O, Walsh DM.
Ann Neurol
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Amyloid ß-protein and beyond: the path forward in Alzheimer's disease.
Authors: Authors: Walsh DM, Selkoe DJ.
Curr Opin Neurobiol
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