Charles Nicholas Serhan

Charles Nicholas Serhan, Ph.D.

Simon Gelman Professor of Anaesthesia
617-525-5001
Publications View
Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation.
Authors: Authors: Chiang N, Fierro IM, Gronert K, Serhan CN.
J Exp Med
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Local and systemic delivery of an aspirin-triggered lipoxin stable analog inhibits neutrophil trafficking.
Authors: Authors: Clish CB, Gronert K, Serhan CN.
Ann N Y Acad Sci
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A novel polyisoprenyl phosphate signaling cascade in human neutrophils.
Authors: Authors: Levy BD, Serhan CN.
Ann N Y Acad Sci
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Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking.
Authors: Authors: Bandeira-Melo C, Bozza PT, Diaz BL, Cordeiro RS, Jose PJ, Martins MA, Serhan CN.
J Immunol
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Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.
Authors: Authors: Serhan CN, Takano T, Chiang N, Gronert K, Clish CB.
Am J Respir Crit Care Med
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A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation.
Authors: Authors: Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM.
J Biol Chem
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Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia.
Authors: Authors: Bandeira-Melo C, Serra MF, Diaz BL, Cordeiro RS, Silva PM, Lenzi HL, Bakhle YS, Serhan CN, Martins MA.
J Immunol
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Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.
Authors: Authors: Serhan CN, Levy BD, Clish CB, Gronert K, Chiang N.
Ernst Schering Res Found Workshop
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Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions.
Authors: Authors: Filep JG, Zouki C, Petasis NA, Hachicha M, Serhan CN.
Blood
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Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Authors: Authors: Titos E, Chiang N, Serhan CN, Romano M, Gaya J, Pueyo G, Clària J.
Am J Physiol
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