Charles Nicholas Serhan

Charles Nicholas Serhan, Ph.D.

Simon Gelman Professor of Anaesthesia
617-525-5001
Publications View
Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-alpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis relevant to periodontal diseases.
Authors: Authors: Pouliot M, Serhan CN.
J Periodontal Res
View full abstract on Pubmed
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
Authors: Authors: Chiang N, Gronert K, Clish CB, O'Brien JA, Freeman MW, Serhan CN.
J Clin Invest
View full abstract on Pubmed
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo.
Authors: Authors: Clish CB, O'Brien JA, Gronert K, Stahl GL, Petasis NA, Serhan CN.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis.
Authors: Authors: Hachicha M, Pouliot M, Petasis NA, Serhan CN.
J Exp Med
View full abstract on Pubmed
Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
Authors: Authors: Levy BD, Fokin VV, Clark JM, Wakelam MJ, Petasis NA, Serhan CN.
FASEB J
View full abstract on Pubmed
LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation.
Authors: Authors: Gewirtz AT, Fokin VV, Petasis NA, Serhan CN, Madara JL.
Am J Physiol
View full abstract on Pubmed
Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators.
Authors: Authors: Serhan CN, Takano T, Gronert K, Chiang N, Clish CB.
Clin Chem Lab Med
View full abstract on Pubmed
Aspirin-triggered 15-epi-lipoxin A4 and stable analogs on lipoxin A4 are potent inhibitors of acute inflammation. Receptors and pathways.
Authors: Authors: Serhan CN, Takano T, Maddox JF.
Adv Exp Med Biol
View full abstract on Pubmed
Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.
Authors: Authors: Serhan CN, Takano T, Clish CB, Gronert K, Petasis N.
Adv Exp Med Biol
View full abstract on Pubmed
Transcellular regulation of eicosanoid biosynthesis.
Authors: Authors: Gronert K, Clish CB, Romano M, Serhan CN.
Methods Mol Biol
View full abstract on Pubmed