Anthony George Letai

Anthony George Letai, M.D., Ph.D.

Professor of Medicine

617-632-2348

Publications

Publications View

Who put the "A" in Atg12: autophagy or apoptosis?

Authors: Authors: Ni Chonghaile T, Letai A.
Mol Cell 2011-12-23
View full abstract on Pubmed

Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.

Authors: Authors: Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, McConkey DJ, Sallan SE, Silverman L, Hirsch MS, Carrasco DR, Letai A.
Science 2011-11-25
View full abstract on Pubmed

Targeting Bcl-2 in CLL: cui bono?

Authors: Authors: Letai A.
Blood 2011-09-29
View full abstract on Pubmed

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Authors: Authors: Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC.
Cell Death Dis 2011-06-23
View full abstract on Pubmed

A new face of BCL-2 inhibition in CLL.

Authors: Authors: Letai A.
Blood 2011-03-10
View full abstract on Pubmed

Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells.

Authors: Authors: Kutuk O, Letai A.
Cell Death Differ 2010-10-01
View full abstract on Pubmed

Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes.

Authors: Authors: Ryan JA, Brunelle JK, Letai A.
Proc Natl Acad Sci U S A 2010-07-20
View full abstract on Pubmed

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

Authors: Authors: Yecies D, Carlson NE, Deng J, Letai A.
Blood 2010-04-22
View full abstract on Pubmed

The landscape of somatic copy-number alteration across human cancers.

Authors: Authors: Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, Greulich H, Reich M, Winckler W, Lawrence MS, Weir BA, Tanaka KE, Chiang DY, Bass AJ, Loo A, Hoffman C, Prensner J, Liefeld T, Gao Q, Yecies D, Signoretti S, Maher E, Kaye FJ, Sasaki H, Tepper JE, Fletcher JA, Tabernero J, Baselga J, Tsao MS, Demichelis F, Rubin MA, Janne PA, Daly MJ, Nucera C, Levine RL, Ebert BL, Gabriel S, Rustgi AK, Antonescu CR, Ladanyi M, Letai A, Garraway LA, Loda M, Beer DG, True LD, Okamoto A, Pomeroy SL, Singer S, Golub TR, Lander ES, Getz G, Sellers WR, Meyerson M.
Nature 2010-02-18
View full abstract on Pubmed

BH3-only proteins and their effects on cancer.

Authors: Authors: Vo TT, Letai A.
Adv Exp Med Biol 2010-01-01
View full abstract on Pubmed