Publications View
Getting away from glucose: fanning the flames of obesity-induced inflammation.
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
Authors: Authors: Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes.
Authors: Authors: Goldfine AB, Silver R, Aldhahi W, Cai D, Tatro E, Lee J, Shoelson SE.
Clin Transl Sci
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Clin Transl Sci
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When a domain is not a domain.
Salsalate improves glycemia and inflammatory parameters in obese young adults.
Authors: Authors: Fleischman A, Shoelson SE, Bernier R, Goldfine AB.
Diabetes Care
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Diabetes Care
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Obesity, inflammation, and insulin resistance.
Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes.
Authors: Authors: Boonyasrisawat W, Eberle D, Bacci S, Zhang YY, Nolan D, Gervino EV, Johnstone MT, Trischitta V, Shoelson SE, Doria A.
Diabetes
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Diabetes
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Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis.
Inflammation and obesity: STAMPing out insulin resistance?
Banking on ATM as a new target in metabolic syndrome.