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Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine
617-732-2528
Publications View
Intermolecular phosphorylation between insulin holoreceptors does not stimulate substrate kinase activity.
Authors: Authors: Lee J, Shoelson SE, Pilch PF.
J Biol Chem
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PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities.
Authors: Authors: Wolf G, Trüb T, Ottinger E, Groninga L, Lynch A, White MF, Miyazaki M, Lee J, Shoelson SE.
J Biol Chem
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L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides.
Authors: Authors: Ye B, Akamatsu M, Shoelson SE, Wolf G, Giorgetti-Peraldi S, Yan X, Roller PP, Burke TR.
J Med Chem
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Interaction of Shc with Grb2 regulates the Grb2 association with mSOS.
Authors: Authors: Ravichandran KS, Lorenz U, Shoelson SE, Burakoff SJ.
Ann N Y Acad Sci
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T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.
Authors: Authors: Fukazawa T, Reedquist KA, Panchamoorthy G, Soltoff S, Trub T, Druker B, Cantley L, Shoelson SE, Band H.
J Biol Chem
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The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase.
Authors: Authors: Fukazawa T, Reedquist KA, Trub T, Soltoff S, Panchamoorthy G, Druker B, Cantley L, Shoelson SE, Band H.
J Biol Chem
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Specificity of the PTB domain of Shc for beta turn-forming pentapeptide motifs amino-terminal to phosphotyrosine.
Authors: Authors: Trüb T, Choi WE, Wolf G, Ottinger E, Chen Y, Weiss M, Shoelson SE.
J Biol Chem
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The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif.
Authors: Authors: Songyang Z, Margolis B, Chaudhuri M, Shoelson SE, Cantley LC.
J Biol Chem
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Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors.
Authors: Authors: Burke TR, Barchi JJ, George C, Wolf G, Shoelson SE, Yan X.
J Med Chem
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A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
Authors: Authors: van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.
Curr Biol
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