Paul B. Yu

Paul Yu, Ph.D., M.D.

Associate Professor of Medicine, Brigham and Women's Hospital
857-307-0390
Publications View
Development of an ALK2-biased BMP type I receptor kinase inhibitor.
Authors: Authors: Mohedas AH, Xing X, Armstrong KA, Bullock AN, Cuny GD, Yu PB.
ACS Chem Biol
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A new class of small molecule inhibitor of BMP signaling.
Authors: Authors: Sanvitale CE, Kerr G, Chaikuad A, Ramel MC, Mohedas AH, Reichert S, Wang Y, Triffitt JT, Cuny GD, Yu PB, Hill CS, Bullock AN.
PLoS One
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Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis.
Authors: Authors: Derwall M, Malhotra R, Lai CS, Beppu Y, Aikawa E, Seehra JS, Zapol WM, Bloch KD, Yu PB.
Arterioscler Thromb Vasc Biol
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Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent.
Authors: Authors: Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY, Xia Y.
PLoS One
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Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice.
Authors: Authors: Steinbicker AU, Bartnikas TB, Lohmeyer LK, Leyton P, Mayeur C, Kao SM, Pappas AE, Peterson RT, Bloch DB, Yu PB, Fleming MD, Bloch KD.
Blood
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Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Authors: Authors: Steinbicker AU, Sachidanandan C, Vonner AJ, Yusuf RZ, Deng DY, Lai CS, Rauwerdink KM, Winn JC, Saez B, Cook CM, Szekely BA, Roy CN, Seehra JS, Cuny GD, Scadden DT, Peterson RT, Bloch KD, Yu PB.
Blood
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Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells.
Authors: Authors: Boergermann JH, Kopf J, Yu PB, Knaus P.
Int J Biochem Cell Biol
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Takotsubo cardiomyopathy complicated by cardiac tamponade: classic hemodynamic findings with a new disease.
Authors: Authors: Yeh RW, Yu PB, Drachman DE.
Circulation
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Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.
Authors: Authors: Kamiya N, Kobayashi T, Mochida Y, Yu PB, Yamauchi M, Kronenberg HM, Mishina Y.
J Bone Miner Res
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p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.
Authors: Authors: De Rosa L, Antonini D, Ferone G, Russo MT, Yu PB, Han R, Missero C.
J Biol Chem
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