Paul B. Yu

Paul Yu, Ph.D., M.D.

Associate Professor of Medicine, Brigham and Women's Hospital
857-307-0390
Publications View
Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP).
Authors: Authors: Smilde BJ, Stockklausner C, Keen R, Whittaker A, Bullock AN, von Delft A, van Schoor NM, Yu PB, Eekhoff EMW.
BMC Musculoskelet Disord
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Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension.
Authors: Authors: Joshi SR, Liu J, Bloom T, Karaca Atabay E, Kuo TH, Lee M, Belcheva E, Spaits M, Grenha R, Maguire MC, Frost JL, Wang K, Briscoe SD, Alexander MJ, Herrin BR, Castonguay R, Pearsall RS, Andre P, Yu PB, Kumar R, Li G.
Sci Rep
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Novel Approaches to Imaging the Pulmonary Vasculature and Right Heart.
Authors: Authors: Alenezi F, Covington TA, Mukherjee M, Mathai SC, Yu PB, Rajagopal S.
Circ Res
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Metabolomic and transcriptomic signatures of chemogenetic heart failure.
Authors: Authors: Spyropoulos F, Sorrentino A, van der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Eroglu E, Saeedi Saravi SS, Yu P, Haigis M, Christou H, Michel T.
Am J Physiol Heart Circ Physiol
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A New Link in the Chain: Unspliced XBP1 in Wnt Signaling and Vascular Calcification.
Authors: Authors: Yang P, Yu PB.
Circ Res
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Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G > A in the ACVR1 gene.
Authors: Authors: Huang X, Roeder A, Li R, Beers J, Liu C, Zou J, Yu PB, Zheng W.
Stem Cell Res
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Sotatercept for Pulmonary Arterial Hypertension.
Authors: Authors: Yang P, Bocobo GA, Yu PB.
N Engl J Med
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A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification.
Authors: Authors: Cong Q, Liu Y, Zhou T, Zhou Y, Xu R, Cheng C, Chung HS, Yan M, Zhou H, Liao Z, Gao B, Bocobo GA, Covington TA, Song HJ, Su P, Yu PB, Yang Y.
Sci Transl Med
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Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
Authors: Authors: Li W, Long L, Yang X, Tong Z, Southwood M, King R, Caruso P, Upton PD, Yang P, Bocobo GA, Nikolic I, Higuera A, Salmon RM, Jiang H, Lodge KM, Hoenderdos K, Baron RM, Yu PB, Condliffe AM, Summers C, Nourshargh S, Chilvers ER, Morrell NW.
Am J Respir Crit Care Med
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Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
Authors: Authors: Williams E, Bagarova J, Kerr G, Xia DD, Place ES, Dey D, Shen Y, Bocobo GA, Mohedas AH, Huang X, Sanderson PE, Lee A, Zheng W, Economides AN, Smith JC, Yu PB, Bullock AN.
JCI Insight
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