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Morris Francis White Jr., Ph.D.

Professor of Pediatrics
Publications View
Trimeprazine increases IRS2 in human islets and promotes pancreatic ß cell growth and function in mice.
Authors: Authors: Kuznetsova A, Yu Y, Hollister-Lock J, Opare-Addo L, Rozzo A, Sadagurski M, Norquay L, Reed JE, El Khattabi I, Bonner-Weir S, Weir GC, Sharma A, White MF.
JCI Insight
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Longevity: Mapping the path to a longer life.
Authors: Authors: White MF.
Nature
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Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.
Authors: Authors: Riehle C, Wende AR, Zhu Y, Oliveira KJ, Pereira RO, Jaishy BP, Bevins J, Valdez S, Noh J, Kim BJ, Moreira AB, Weatherford ET, Manivel R, Rawlings TA, Rech M, White MF, Abel ED.
Mol Cell Biol
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APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.
Authors: Authors: Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, White MF, Liu F, Dong LQ.
Cell Rep
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Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
Authors: Authors: Hançer NJ, Qiu W, Cherella C, Li Y, Copps KD, White MF.
J Biol Chem
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Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis.
Authors: Authors: Sadagurski M, Dong XC, Myers MG, White MF.
Mol Metab
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IRS1Ser³°7 phosphorylation does not mediate mTORC1-induced insulin resistance.
Authors: Authors: Herrema H, Lee J, Zhou Y, Copps KD, White MF, Ozcan U.
Biochem Biophys Res Commun
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Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
Authors: Authors: Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Rech M, Sheng X, Weimer BC, Gottlieb RA, White MF, Abel ED.
J Clin Invest
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Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38a MAPK during insulin resistance.
Authors: Authors: Qi Y, Xu Z, Zhu Q, Thomas C, Kumar R, Feng H, Dostal DE, White MF, Baker KM, Guo S.
Diabetes
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Nerve growth factor receptor TrkA, a new receptor in insulin signaling pathway in PC12 cells.
Authors: Authors: Geetha T, Rege SD, Mathews SE, Meakin SO, White MF, Babu JR.
J Biol Chem
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