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Morris Francis White Jr., Ph.D.

Professor of Pediatrics
617-732-2578
Publications View
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.
Authors: Authors: Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, Wright CV, White MF, Arden KC, Accili D.
J Clin Invest
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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
Authors: Authors: Rui L, Yuan M, Frantz D, Shoelson S, White MF.
J Biol Chem
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Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: therapeutic implications.
Authors: Authors: Chang Q, Li Y, White MF, Fletcher JA, Xiao S.
Cancer Res
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Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.
Authors: Authors: Xuan S, Kitamura T, Nakae J, Politi K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A.
J Clin Invest
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IRS proteins and the common path to diabetes.
Authors: Authors: White MF.
Am J Physiol Endocrinol Metab
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Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL.
Authors: Authors: Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ.
J Biol Chem
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Pdx1 restores beta cell function in Irs2 knockout mice.
Authors: Authors: Kushner JA, Ye J, Schubert M, Burks DJ, Dow MA, Flint CL, Dutta S, Wright CV, Montminy MR, White MF.
J Clin Invest
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Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway.
Authors: Authors: Xiao H, Yin T, Wang XY, Uchida T, Chung J, White MF, Yang YC.
J Biol Chem
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Insulin signaling after exercise in insulin receptor substrate-2-deficient mice.
Authors: Authors: Howlett KF, Sakamoto K, Hirshman MF, Aschenbach WG, Dow M, White MF, Goodyear LJ.
Diabetes
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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action.
Authors: Authors: Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF.
J Biol Chem
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