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Loren David Walensky, M.D., Ph.D.

Professor of Pediatrics
617-355-6369
Publications View
Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK.
Authors: Authors: Katz SG, Fisher JK, Correll M, Bronson RT, Ligon KL, Walensky LD.
Oncogene
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Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.
Authors: Authors: Edwards AL, Gavathiotis E, LaBelle JL, Braun CR, Opoku-Nsiah KA, Bird GH, Walensky LD.
Chem Biol
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The retinoblastoma protein induces apoptosis directly at the mitochondria.
Authors: Authors: Hilgendorf KI, Leshchiner ES, Nedelcu S, Maynard MA, Calo E, Ianari A, Walensky LD, Lees JA.
Genes Dev
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Playing fullBAK.
Authors: Authors: Walensky LD.
Cell Cycle
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Direct BAKtivation.
Authors: Authors: Walensky LD.
Nat Struct Mol Biol
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Direct activation of full-length proapoptotic BAK.
Authors: Authors: Leshchiner ES, Braun CR, Bird GH, Walensky LD.
Proc Natl Acad Sci U S A
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Protein-protein interactions: A PUMA mechanism unfolds.
Authors: Authors: Walensky LD.
Nat Chem Biol
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A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival.
Authors: Authors: Cohen NA, Stewart ML, Gavathiotis E, Tepper JL, Bruekner SR, Koss B, Opferman JT, Walensky LD.
Chem Biol
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Targeted disruption of the BCL9/ß-catenin complex inhibits oncogenic Wnt signaling.
Authors: Authors: Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR.
Sci Transl Med
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Interview with Loren D Walensky.
Authors: Authors: Walensky LD.
Future Med Chem
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