Loren David Walensky

Loren David Walensky, M.D., Ph.D.

Professor of Pediatrics

617-355-6369

Publications

Publications View

Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.

Authors: Authors: Bird GH, Irimia A, Ofek G, Kwong PD, Wilson IA, Walensky LD.
Nat Struct Mol Biol 2014-12-01
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Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.

Authors: Authors: Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, Look AT, Walensky LD, Kelliher MA, Gutierrez A.
Leukemia 2014-09-01
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Hydrocarbon-stapled peptides: principles, practice, and progress.

Authors: Authors: Walensky LD, Bird GH.
J Med Chem 2014-08-14
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Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection.

Authors: Authors: Bird GH, Boyapalle S, Wong T, Opoku-Nsiah K, Bedi R, Crannell WC, Perry AF, Nguyen H, Sampayo V, Devareddy A, Mohapatra S, Mohapatra SS, Walensky LD.
J Clin Invest 2014-05-01
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Distinct BimBH3 (BimSAHB) stapled peptides for structural and cellular studies.

Authors: Authors: Bird GH, Gavathiotis E, LaBelle JL, Katz SG, Walensky LD.
ACS Chem Biol 2014-03-21
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Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells.

Authors: Authors: Katz SG, Labelle JL, Meng H, Valeriano RP, Fisher JK, Sun H, Rodig SJ, Kleinstein SH, Walensky LD.
Blood 2014-02-06
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Photoreactive stapled peptides to identify and characterize BCL-2 family interaction sites by mass spectrometry.

Authors: Authors: Lee S, Braun CR, Bird GH, Walensky LD.
Methods Enzymol 2014-01-01
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A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators.

Authors: Authors: Szlyk B, Braun CR, Ljubicic S, Patton E, Bird GH, Osundiji MA, Matschinsky FM, Walensky LD, Danial NN.
Nat Struct Mol Biol 2014-01-01
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Evaluation and critical assessment of putative MCL-1 inhibitors.

Authors: Authors: Varadarajan S, Vogler M, Butterworth M, Dinsdale D, Walensky LD, Cohen GM.
Cell Death Differ 2013-11-01
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Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.

Authors: Authors: Kim W, Bird GH, Neff T, Guo G, Kerenyi MA, Walensky LD, Orkin SH.
Nat Chem Biol 2013-10-01
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