Dominic M. Walsh

Dominic M. Walsh, Ph.D.

Lecturer on Neurology

617-525-5059

Publications

Publications View

Aberrant protein structure and diseases of the brain.

Authors: Authors: Welzel AT, Walsh DM.
Ir J Med Sci 2011-03-01
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Isolation of low-n amyloid ß-protein oligomers from cultured cells, CSF, and brain.

Authors: Authors: Shankar GM, Welzel AT, McDonald JM, Selkoe DJ, Walsh DM.
Methods Mol Biol 2011-01-01
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Macroautophagy is not directly involved in the metabolism of amyloid precursor protein.

Authors: Authors: Boland B, Smith DA, Mooney D, Jung SS, Walsh DM, Platt FM.
J Biol Chem 2010-11-26
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Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.

Authors: Authors: O'Nuallain B, Freir DB, Nicoll AJ, Risse E, Ferguson N, Herron CE, Collinge J, Walsh DM.
J Neurosci 2010-10-27
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Biological markers of amyloid beta-related mechanisms in Alzheimer's disease.

Authors: Authors: Hampel H, Shen Y, Walsh DM, Aisen P, Shaw LM, Zetterberg H, Trojanowski JQ, Blennow K.
Exp Neurol 2010-06-01
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The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

Authors: Authors: Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM.
Brain 2010-05-01
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beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.

Authors: Authors: Sala Frigerio C, Fadeeva JV, Minogue AM, Citron M, Van Leuven F, Staufenbiel M, Paganetti P, Selkoe DJ, Walsh DM.
FEBS J 2010-03-01
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Amyloid ß-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process.

Authors: Authors: Hellstrand E, Boland B, Walsh DM, Linse S.
ACS Chem Neurosci 2010-01-20
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An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.

Authors: Authors: Sala Frigerio C, Kukar TL, Fauq A, Engel PC, Golde TE, Walsh DM.
Biochemistry 2009-11-24
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Alzheimer's disease: synaptic dysfunction and Abeta.

Authors: Authors: Shankar GM, Walsh DM.
Mol Neurodegener 2009-11-23
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