Dominic M. Walsh

Dominic M. Walsh, Ph.D.

Lecturer on Neurology

617-525-5059

Publications

Publications View

Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.

Authors: Authors: Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A.
Cancer Cell 2017-01-09
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Large Soluble Oligomers of Amyloid ß-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.

Authors: Authors: Yang T, Li S, Xu H, Walsh DM, Selkoe DJ.
J Neurosci 2017-01-04
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The Aggregation Paths and Products of Aß42 Dimers Are Distinct from Those of the Aß42 Monomer.

Authors: Authors: O'Malley TT, Witbold WM, Linse S, Walsh DM.
Biochemistry 2016-11-08
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Non-Fibrillar Oligomeric Amyloid-ß within Synapses.

Authors: Authors: Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL.
J Alzheimers Dis 2016-05-30
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A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration.

Authors: Authors: Walsh DM, Selkoe DJ.
Nat Rev Neurosci 2016-04-01
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Soluble Aß oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance.

Authors: Authors: Lei M, Xu H, Li Z, Wang Z, O'Malley TT, Zhang D, Walsh DM, Xu P, Selkoe DJ, Li S.
Neurobiol Dis 2016-01-01
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N-Terminal Extensions Retard Aß42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aß42.

Authors: Authors: Szczepankiewicz O, Linse B, Meisl G, Thulin E, Frohm B, Sala Frigerio C, Colvin MT, Jacavone AC, Griffin RG, Knowles T, Walsh DM, Linse S.
J Am Chem Soc 2015-11-25
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The aqueous phase of Alzheimer's disease brain contains assemblies built from ~4 and ~7 kDa Aß species.

Authors: Authors: Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM, Frosch MP, Walsh DM.
Alzheimers Dement 2015-11-01
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Targeted Magnetic Nanoparticles for Remote Magnetothermal Disruption of Amyloid-ß Aggregates.

Authors: Authors: Loynachan CN, Romero G, Christiansen MG, Chen R, Ellison R, O'Malley TT, Froriep UP, Walsh DM, Anikeeva P.
Adv Healthc Mater 2015-10-01
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Anti-Aß antibodies incapable of reducing cerebral Aß oligomers fail to attenuate spatial reference memory deficits in J20 mice.

Authors: Authors: Mably AJ, Liu W, Mc Donald JM, Dodart JC, Bard F, Lemere CA, O'Nuallain B, Walsh DM.
Neurobiol Dis 2015-10-01
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