Publications View
Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation.
Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration.
Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo.
Authors: Authors: Klyubin I, Walsh DM, Cullen WK, Fadeeva JV, Anwyl R, Selkoe DJ, Rowan MJ.
Eur J Neurosci
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Eur J Neurosci
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Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as wel…
Authors: Authors: Wang Q, Walsh DM, Rowan MJ, Selkoe DJ, Anwyl R.
J Neurosci
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J Neurosci
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Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.
Authors: Authors: Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ.
Neuron
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Neuron
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Soluble oligomers for the diagnosis of neurodegenerative diseases.
gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.
Authors: Authors: Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ.
Biochemistry
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Biochemistry
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The 8th International Conference on Alzheimer's Disease and Related Disorders, July 20-25, 2002, Stockholm, Sweden.
Authors: Authors: Kimberly WT, Kovacs DM, Walsh D, Lashuel H, Lemere CA.
Amyloid
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Amyloid
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The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.
Authors: Authors: Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ.
Neuron
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Neuron
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Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition.
Authors: Authors: Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ.
Biochem Soc Trans
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Biochem Soc Trans
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