Publications View
Antiinflammatory potential of lipoxygenase-derived eicosanoids: a molecular switch at 5 and 15 positions?
Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor.
Authors: Authors: Maddox JF, Hachicha M, Takano T, Petasis NA, Fokin VV, Serhan CN.
J Biol Chem
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J Biol Chem
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Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell-cell interactions or a therapeutic opportunity?
Transcellular pathways and cell adhesion as potential contributors to leukotriene and lipoxin biosynthesis in acute glomerulonephritis.
Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
Lipoxin metabolism by human promyelocytic leukemia (HL-60) cells.
Characterisation of the binding of leukotriene B4 to macrophages of the rainbow trout Oncorhynchus mykiss.
Authors: Authors: Bowden LA, Fiore S, Restall CJ, Serhan CN, Rowley AF.
J Exp Biol
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J Exp Biol
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Inflammation. Signalling the fat controller.
Activation of human monocytes and the acute monocytic leukemia cell line (THP-1) by lipoxins involves unique signaling pathways for lipoxin A4 versus lipoxin B4: evidence for differential Ca2+ mobilization.
Aspirin-triggered lipoxins (15-epi-LX) are generated by the human lung adenocarcinoma cell line (A549)-neutrophil interactions and are potent inhibitors of cell proliferation.