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Loren David Walensky, M.D., Ph.D.

Professor of Pediatrics
617-355-6369
Publications View
A stapled BID BH3 helix directly binds and activates BAX.
Authors: Authors: Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ.
Mol Cell
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BCL-2 in the crosshairs: tipping the balance of life and death.
Authors: Authors: Walensky LD.
Cell Death Differ
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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Authors: Authors: Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ.
Science
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Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.
Authors: Authors: MacGinnitie AJ, Walensky LD, Turvey SE, Orange JS, Bonilla FA, Silverman LB, Oettgen H.
Pediatr Allergy Immunol
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Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron.
Authors: Authors: Ramez M, Blot-Chabaud M, Cluzeaud F, Chanan S, Patterson M, Walensky LD, Marfatia S, Baines AJ, Chasis JA, Conboy JG, Mohandas N, Gascard P.
Kidney Int
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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
Authors: Authors: Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ.
Cancer Cell
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Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.
Authors: Authors: Shen L, Liang F, Walensky LD, Huganir RL.
J Neurosci
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Molecular and functional characterization of protein 4.1B, a novel member of the protein 4.1 family with high level, focal expression in brain.
Authors: Authors: Parra M, Gascard P, Walensky LD, Gimm JA, Blackshaw S, Chan N, Takakuwa Y, Berger T, Lee G, Chasis JA, Snyder SH, Mohandas N, Conboy JG.
J Biol Chem
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Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor.
Authors: Authors: Ye K, Compton DA, Lai MM, Walensky LD, Snyder SH.
J Neurosci
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A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1.
Authors: Authors: Walensky LD, Blackshaw S, Liao D, Watkins CC, Weier HU, Parra M, Huganir RL, Conboy JG, Mohandas N, Snyder SH.
J Neurosci
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