Cigall Kadoch

Cigall Kadoch, Ph.D.

Assistant Professor of Pediatrics
Publications View
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.
Authors: Authors: McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C.
Cancer Cell
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Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens.
Authors: Authors: Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE, Wells JN, Cassel SH, Vazquez F, Weir BA, Hahn WC, Marsh JA, Tsherniak A, Kadoch C.
Cell Syst
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Disruption of mammalian SWI/SNF and polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities.
Authors: Authors: McBride MJ, Kadoch C.
J Pathol
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A Two-Faced mSWI/SNF Subunit: Dual Roles for ARID1A in Tumor Suppression and Oncogenicity in the Liver.
Authors: Authors: Otto JE, Kadoch C.
Cancer Cell
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SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Authors: Authors: Nakayama RT, Pulice JL, Valencia AM, McBride MJ, McKenzie ZM, Gillespie MA, Ku WL, Teng M, Cui K, Williams RT, Cassel SH, Qing H, Widmer CJ, Demetri GD, Irizarry RA, Zhao K, Ranish JA, Kadoch C.
Nat Genet
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Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain.
Authors: Authors: Boulay G, Sandoval GJ, Riggi N, Iyer S, Buisson R, Naigles B, Awad ME, Rengarajan S, Volorio A, McBride MJ, Broye LC, Zou L, Stamenkovic I, Kadoch C, Rivera MN.
Cell
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A SMARCD2-containing mSWI/SNF complex is required for granulopoiesis.
Authors: Authors: Michel BC, Kadoch C.
Nat Genet
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TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin.
Authors: Authors: Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR.
Nat Struct Mol Biol
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Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities.
Authors: Authors: St Pierre R, Kadoch C.
Curr Opin Genet Dev
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Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin.
Authors: Authors: Stanton BZ, Hodges C, Calarco JP, Braun SM, Ku WL, Kadoch C, Zhao K, Crabtree GR.
Nat Genet
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