Picture of Charles Richardson

Charles Clifton Richardson, M.D.

Edward S. Wood Professor of Biological Chemistry and Molecular Pharmacology, Emeritus
617-432-1864
Richardson lab website

Fig. 1Fig. 1A major goal is to define, in molecular terms, the mechanism by which a chromosome is replicated. The replication of the chromosome of bacteriophage T7 has been used as a model system.  T7 has evolved an efficient and economical system for DNA replication.  The cartoon depicts the T7 replisome and illustrates the major molecular motors and contacts. On the leading strand, T7 DNA polymerase (gp5) undergoes multiple conformational changes as it moves from one template position to another and senses the correct fit of an incoming deoxyribonucleoside triphosphate.  E. coli thioredoxin (trxbinds tightly to the thumb subdomain of gp5 and increases its processivity 100-fold.  The interaction with gp5 also creates docking sites for the other T7 replication proteins.  Unwinding of the DNA to create a ssDNA template for gp5/trx is accomplished by the helicase located in the C-terminal half of T7 gene 4 protein (gp4). Gp4 assembles as a hexamer on the lagging strand and uses the energy of hydrolysis of dTTP to translocate 5’ – 3’ on ssDNA; it unwinds duplex DNA that it encounters. The assembly of the hexamer creates six NTP-binding sites at the interface of the subunits; nucleotide hydrolysis results in conformational changes that are conveyed to the central core through which the DNA passes.

In order for the lagging strand to be replicated it is necessary to periodically synthesize an RNA primer.  Primer synthesis is catalyzed by the primase located in the N-terminal half of gp4. The tetraribonucleotides, synthesized at specific DNA sequences, are extended by a lagging strand polymerase to generate Okazaki fragments several thousand nucleotides in length.  The lagging strand folds back on itself such that the lagging strand DNA polymerase can interact with the helicase.  This association of the two polymerases enables both strands to be synthesized in the same overall direction and synthesis of both strands now proceeds at identical rates. The folding of the lagging strand creates a replication loop of lagging strand DNA that contains the nascent Okazaki fragment. These loops, visualized by electron microscopy or real time single molecule techniques, form, grow, and resolve, to generate Okazaki fragments of uniform lengths of around 1000 nucleotides.  Upon initiation of primer synthesis the helicase halts movement. This brake mechanism is dependent on the interaction of the primase with the helicase.

Although proteins in the T7 replisome are relatively few, there are a large number of interactions that provide for the molecular motors and switches. All of the individual proteins have been crystallized and their crystal structures determined. In addition, a snapshot of an actively synthesizing polymerase is available in the crystal structure of gp5/trx in complex with a primer-template and a dNTP. The structure of the full length hexameric gp4 and those of the helicase and primase domains provide insight into the communication between the domains as well as the mechanism of translocation of the helicase on DNA.

In addition to these studies on the replisome studies are designed to understand the acquisition of host functions by T7.  T7 derives the nucleotide precursors for DNA synthesis from the breakdown of the host DNA.  T7 gene 1.7 protein is a nucleotide kinase that converts dTMP and dGMP to dTDP and dGDP that are then converted to the dNTP by host kinases.  E. coli adenylate kinase and dCMP kinase account for the formation of dADP and dCDP.  T7 gene 1.2 protein inhibits an E. coli  dGTPase that hydrolyzes dGTP to dG and tripolyphosphate.  Gene 2 protein binds to the Beta subunit if E. coli RNA polymerase and inhibits its activity, a prerequisite for packaging of the DNA.

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Room C2-219

240 Longwood Avenue

Boston, MA 02115

Publications View
Observation of Charge-Dependent Azimuthal Correlations in p-Pb Collisions and Its Implication for the Search for the Chiral Magnetic Effect.
Authors: Authors: Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Waltenberger W, Wulz CE, Dvornikov O, Makarenko V, Zykunov V, Mossolov V, Shumeiko N, Suarez Gonzalez J, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Vannerom D, Yonamine R, Zenoni F, Zhang F, Cimmino A, Cornelis T, Dobur D, Fagot A, Garcia G, Gul M, Khvastunov I, Poyraz D, Salva S, Schöfbeck R, Sharma A, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Francois B, Giammanco A, Jafari A, Jez P, Komm M, Krintiras G, Lemaitre V, Magitteri A, Mertens A, Musich M, Nuttens C, Piotrzkowski K, Quertenmont L, Selvaggi M, Vidal Marono M, Wertz S, Beliy N, Aldá Júnior WL, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Rebello Teles P, Belchior Batista Das Chagas E, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, Fonseca De Souza S, Huertas Guativa LM, Malbouisson H, Matos Figueiredo D, Mora Herrera C, Mundim L, Nogima H, Prado Da Silva WL, Santoro A, Sznajder A, Tonelli Manganote EJ, Vilela Pereira A, Ahuja S, Bernardes CA, Dogra S, Fernandez Perez Tomei TR, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Romero Abad D, Ruiz Vargas JC, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Chaparro Sierra LF, Florez C, Gomez JP, González Hernández CF, Ruiz Alvarez JD, Sanabria JC, Godinovic N, Lelas D, Puljak I, Ribeiro Cipriano PM, Sculac T, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Mesic B, Micanovic S, Sudic L, Susa T, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Tsiakkouri D, Finger M, Finger M, Carrera Jarrin E, Abdelalim AA, Mohammed Y, Salama E, Kadastik M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Järvinen T, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, Hamel de Monchenault G, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Zghiche A, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, Granier de Cassagnac R, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Strebler T, Yilmaz Y, Zabi A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Le Bihan AC, Skovpen K, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Bouvier E, Carrillo Montoya CA, Chierici R, Contardo D, Courbon B, Depasse P, El Mamouni H, Fan J, Fay J, Gascon S, Gouzevitch M, Grenier G, et al.
Phys Rev Lett
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Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers.
Authors: Authors: Zhu B, Wang L, Mitsunobu H, Lu X, Hernandez AJ, Yoshida-Takashima Y, Nunoura T, Tabor S, Richardson CC.
Proc Natl Acad Sci U S A
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Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.
Authors: Authors: Kulczyk AW, Moeller A, Meyer P, Sliz P, Richardson CC.
Proc Natl Acad Sci U S A
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Kinetics of Lagging-strand DNA Synthesis In Vitro by the Bacteriophage T7 Replication Proteins.
Authors: Authors: Hernandez AJ, Richardson CC.
J Vis Exp
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Search for Dark Matter and Supersymmetry with a Compressed Mass Spectrum in the Vector Boson Fusion Topology in Proton-Proton Collisions at sqrt[s]=8??TeV.
Authors: Authors: Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Treberer-Treberspurg W, Waltenberger W, Wulz CE, Mossolov V, Shumeiko N, Suarez Gonzalez J, Alderweireldt S, Cornelis T, De Wolf EA, Janssen X, Knutsson A, Lauwers J, Luyckx S, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Heracleous N, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Caillol C, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Yonamine R, Zenoni F, Zhang F, Cimmino A, Dobur D, Fagot A, Garcia G, Gul M, Mccartin J, Poyraz D, Salva S, Schöfbeck R, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, Ceard L, De Visscher S, Delaere C, Delcourt M, Forthomme L, Francois B, Giammanco A, Jafari A, Jez P, Komm M, Lemaitre V, Magitteri A, Mertens A, Musich M, Nuttens C, Piotrzkowski K, Quertenmont L, Selvaggi M, Vidal Marono M, Wertz S, Beliy N, Aldá Júnior WL, Alves FL, Alves GA, Brito L, Correa Martins Junior M, Hensel C, Moraes A, Pol ME, Rebello Teles P, Belchior Batista Das Chagas E, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, Fonseca De Souza S, Huertas Guativa LM, Malbouisson H, Matos Figueiredo D, Mora Herrera C, Mundim L, Nogima H, Prado Da Silva WL, Santoro A, Sznajder A, Tonelli Manganote EJ, Vilela Pereira A, Ahuja S, Bernardes CA, Dogra S, Fernandez Perez Tomei TR, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Romero Abad D, Ruiz Vargas JC, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Du R, Jiang CH, Leggat D, Liu Z, Romeo F, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Asawatangtrakuldee C, Ban Y, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Chaparro Sierra LF, Florez C, Gomez JP, Ruiz Alvarez JD, Sanabria JC, Godinovic N, Lelas D, Puljak I, Ribeiro Cipriano PM, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Luetic J, Micanovic S, Sudic L, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Finger M, Finger M, Carrera Jarrin E, Awad A, Elgammal S, Mohamed A, Salama E, Calpas B, Kadastik M, Murumaa M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Peltola T, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, Hamel de Monchenault G, Jarry P, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Zghiche A, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, Granier de Cassagnac R, Jo M, Lisniak S, Miné P, Naranjo IN, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Strebler T, Yilmaz Y, Zabi A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Le Bihan AC, Merlin JA, Skovpen K, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Bouvier E, Carrillo Montoya CA, Chierici R, Contardo D, Courbon B, Depasse P, El Mamouni H, Fan J, Fay J, Gascon S, et al.
Phys Rev Lett
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Suppression and azimuthal anisotropy of prompt and nonprompt [Formula: see text] production in PbPb collisions at [Formula: see text][Formula: see text].
Authors: Authors: Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Waltenberger W, Wulz CE, Dvornikov O, Makarenko V, Zykunov V, Mossolov V, Shumeiko N, Suarez Gonzalez J, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Vannerom D, Yonamine R, Zenoni F, Zhang F, Cimmino A, Cornelis T, Dobur D, Fagot A, Garcia G, Gul M, Khvastunov I, Poyraz D, Salva S, Schöfbeck R, Sharma A, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Francois B, Giammanco A, Jafari A, Jez P, Komm M, Krintiras G, Lemaitre V, Magitteri A, Mertens A, Musich M, Nuttens C, Piotrzkowski K, Quertenmont L, Selvaggi M, Vidal Marono M, Wertz S, Beliy N, Aldá Júnior WL, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Rebello Teles P, Chagas EBBD, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, De Souza SF, Guativa LMH, Malbouisson H, Matos Figueiredo D, Mora Herrera C, Mundim L, Nogima H, Prado Da Silva WL, Santoro A, Sznajder A, Tonelli Manganote EJ, Vilela Pereira A, Ahuja S, Bernardes CA, Dogra S, Fernandez Perez Tomei TR, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Romero Abad D, Ruiz Vargas JC, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Chaparro Sierra LF, Florez C, Gomez JP, González Hernández CF, Ruiz Alvarez JD, Sanabria JC, Godinovic N, Lelas D, Puljak I, Ribeiro Cipriano PM, Sculac T, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Micanovic S, Sudic L, Susa T, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Tsiakkouri D, Finger M, Finger M, Jarrin EC, Kamel AE, Mahmoud MA, Radi A, Kadastik M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Järvinen T, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, Hamel de Monchenault G, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Zghiche A, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, Granier de Cassagnac R, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Strebler T, Yilmaz Y, Zabi A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Le Bihan AC, Skovpen K, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Bouvier E, Carrillo Montoya CA, Chierici R, Contardo D, Courbon B, Depasse P, El Mamouni H, Fan J, Fay J, Gascon S, Gouzevitch M, Grenier G, Ille B, Lagarde F, Laktineh IB, Lethuillier M, et al.
Eur Phys J C Part Fields
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Measurement of double-differential cross sections for top quark pair production in pp collisions at [Formula: see text][Formula: see text] and impact on parton distribution functions.
Authors: Authors: Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Waltenberger W, Wulz CE, Dvornikov O, Makarenko V, Mossolov V, Suarez Gonzalez J, Zykunov V, Shumeiko N, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Skovpen K, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Vannerom D, Yonamine R, Zenoni F, Zhang F, Cornelis T, Dobur D, Fagot A, Gul M, Khvastunov I, Poyraz D, Salva S, Schöfbeck R, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Francois B, Giammanco A, Jafari A, Komm M, Krintiras G, Lemaitre V, Magitteri A, Mertens A, Musich M, Piotrzkowski K, Quertenmont L, Selvaggi M, Vidal Marono M, Wertz S, Beliy N, Aldá Júnior WL, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Rebello Teles P, Chagas EBBD, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, De Souza SF, Guativa LMH, Malbouisson H, Matos Figueiredo D, Mora Herrera C, Mundim L, Nogima H, Prado Da Silva WL, Santoro A, Sznajder A, Tonelli Manganote EJ, Torres Da Silva De Araujo F, Vilela Pereira A, Ahuja S, Bernardes CA, Dogra S, Fernandez Perez Tomei TR, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Romero Abad D, Ruiz Vargas JC, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Ruan M, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Chaparro Sierra LF, Florez C, Gomez JP, González Hernández CF, Ruiz Alvarez JD, Sanabria JC, Godinovic N, Lelas D, Puljak I, Ribeiro Cipriano PM, Sculac T, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Mesic B, Susa T, Ather MW, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Finger M, Finger M, Carrera Jarrin E, Ellithi Kamel A, Mahmoud MA, Radi A, Kadastik M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Järvinen T, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, Hamel de Monchenault G, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, Granier de Cassagnac R, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Stahl Leiton AG, Strebler T, Yilmaz Y, Zabi A, Zghiche A, Agram JL, Andrea J, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Bihan AL, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Carrillo Montoya CA, Chierici R, Contardo D, Courbon B, Depasse P, El Mamouni H, Fay J, Finco L, Gascon S, Gouzevitch M, Grenier G, Ille B, Lagarde F, Laktineh IB, Lethuillier M, Mirabito L, Pequegnot AL, Perries S, Popov A, et al.
Eur Phys J C Part Fields
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Measurement of the production cross section of a W boson in association with two b jets in pp collisions at [Formula: see text].
Authors: Authors: Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Treberer-Treberspurg W, Waltenberger W, Wulz CE, Mossolov V, Shumeiko N, Gonzalez JS, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Zeid SA, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Heracleous N, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Caillol C, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Velde CV, Vanlaer P, Yonamine R, Zenoni F, Zhang F, Cimmino A, Cornelis T, Dobur D, Fagot A, Garcia G, Gul M, Poyraz D, Salva S, Schöfbeck R, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Forthomme L, Francois B, Giammanco A, Jafari A, Jez P, Komm M, Lemaitre V, Magitteri A, Mertens A, Musich M, Nuttens C, Piotrzkowski K, Quertenmont L, Selvaggi M, Marono MV, Wertz S, Beliy N, Júnior WLA, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Teles PR, Chagas EBBD, Carvalho W, Chinellato J, Custódio A, Costa EMD, Silveira GGD, Damiao DJ, Martins CO, De Souza SF, Guativa LMH, Malbouisson H, Figueiredo DM, Herrera CM, Mundim L, Nogima H, Silva WLPD, Santoro A, Sznajder A, Manganote EJT, Pereira AV, Ahuja S, Bernardes CA, Dogra S, Tomei TRFP, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Abad DR, Vargas JCR, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Sierra LFC, Florez C, Gomez JP, Hernández CFG, Alvarez JDR, Sanabria JC, Godinovic N, Lelas D, Puljak I, Cipriano PMR, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Micanovic S, Sudic L, Susa T, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Finger M, Finger M, Jarrin EC, Assran Y, Elkafrawy T, Mahrous A, Calpas B, Kadastik M, Murumaa M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Peltola T, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, de Monchenault GH, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Zghiche A, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, de Cassagnac RG, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Strebler T, Yilmaz Y, Zabi A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Bihan AL, Merlin JA, Skovpen K, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Bouvier E, Montoya CAC, Chierici R, Contardo D, Courbon B, Depasse P, Mamouni HE, Fan J, Fay J, Gascon S, Gouzevitch M, Grenier G, Ille B, Lagarde F, Laktineh IB, Lethuillier M, Mirabito L, Pequegnot AL, Perries S, Popov A, Sabes D, Sordini V, Donckt MV, Verdier P, Viret S, Toriashvili T, Bagaturia I, Autermann C, Beranek S, Feld L, Heister A, Kiesel MK, et al.
Eur Phys J C Part Fields
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Measurement of the WZ production cross section in pp collisions at [Formula: see text] and 8[Formula: see text] and search for anomalous triple gauge couplings at [Formula: see text].
Authors: Authors: Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Treberer-Treberspurg W, Waltenberger W, Wulz CE, Mossolov V, Shumeiko N, Gonzalez JS, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Zeid SA, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Heracleous N, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Caillol C, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Yonamine R, Zenoni F, Zhang F, Cimmino A, Cornelis T, Dobur D, Fagot A, Garcia G, Gul M, Poyraz D, Salva S, Schöfbeck R, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Forthomme L, Francois B, Giammanco A, Jafari A, Jez P, Komm M, Lemaitre V, Magitteri A, Mertens A, Musich M, Nuttens C, Piotrzkowski K, Quertenmont L, Selvaggi M, Marono MV, Wertz S, Beliy N, Júnior WLA, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Teles PR, Chagas EBBD, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, De Souza SF, Guativa LMH, Malbouisson H, Figueiredo DM, Herrera CM, Mundim L, Nogima H, Da Silva WLP, Santoro A, Sznajder A, Manganote EJT, Pereira AV, Ahuja S, Bernardes CA, Dogra S, Tomei TRFP, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Abad DR, Vargas JCR, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Sierra LFC, Florez C, Gomez JP, Hernández CFG, Alvarez JDR, Sanabria JC, Godinovic N, Lelas D, Puljak I, Cipriano PMR, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Micanovic S, Sudic L, Susa T, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Finger M, Finger M, Jarrin EC, Elgammal S, Mohamed A, Salama E, Calpas B, Kadastik M, Murumaa M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Peltola T, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, de Monchenault GH, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Zghiche A, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, de Cassagnac RG, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Strebler T, Yilmaz Y, Zabi A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Le Bihan AC, Merlin JA, Skovpen K, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Bouvier E, Montoya CAC, Chierici R, Contardo D, Courbon B, Depasse P, Mamouni HE, Fan J, Fay J, Gascon S, Gouzevitch M, Grenier G, Ille B, Lagarde F, Laktineh IB, Lethuillier M, Mirabito L, Pequegnot AL, Perries S, Popov A, Sabes D, Sordini V, Vander Donckt M, Verdier P, Viret S, Toriashvili T, Tsamalaidze Z, Autermann C, et al.
Eur Phys J C Part Fields
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Measurement of the top quark mass using single top quark events in proton-proton collisions at [Formula: see text] TeV.
Authors: Authors: Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, König A, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rad N, Rahbaran B, Rohringer H, Schieck J, Strauss J, Waltenberger W, Wulz CE, Dvornikov O, Makarenko V, Mossolov V, Gonzalez JS, Zykunov V, Shumeiko N, Alderweireldt S, De Wolf EA, Janssen X, Lauwers J, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Lowette S, Moortgat S, Moreels L, Olbrechts A, Python Q, Skovpen K, Tavernier S, Van Doninck W, Van Mulders P, Van Parijs I, Brun H, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Goldouzian R, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Luetic J, Maerschalk T, Marinov A, Randle-Conde A, Seva T, Vander Velde C, Vanlaer P, Vannerom D, Yonamine R, Zenoni F, Zhang F, Cimmino A, Cornelis T, Dobur D, Fagot A, Gul M, Khvastunov I, Poyraz D, Salva S, Schöfbeck R, Tytgat M, Van Driessche W, Yazgan E, Zaganidis N, Bakhshiansohi H, Beluffi C, Bondu O, Brochet S, Bruno G, Caudron A, De Visscher S, Delaere C, Delcourt M, Francois B, Giammanco A, Jafari A, Komm M, Krintiras G, Lemaitre V, Magitteri A, Mertens A, Musich M, Piotrzkowski K, Quertenmont L, Selvaggi M, Marono MV, Wertz S, Beliy N, Aldá Júnior WL, Alves FL, Alves GA, Brito L, Hensel C, Moraes A, Pol ME, Rebello Teles P, Belchior Batista Das Chagas E, Carvalho W, Chinellato J, Custódio A, Da Costa EM, Da Silveira GG, De Jesus Damiao D, De Oliveira Martins C, Fonseca De Souza S, Huertas Guativa LM, Malbouisson H, Matos Figueiredo D, Mora Herrera C, Mundim L, Nogima H, Prado Da Silva WL, Santoro A, Sznajder A, Tonelli Manganote EJ, Torres Da Silva De Araujo F, Vilela Pereira A, Ahuja S, Bernardes CA, Dogra S, Fernandez Perez Tomei TR, Gregores EM, Mercadante PG, Moon CS, Novaes SF, Padula SS, Romero Abad D, Ruiz Vargas JC, Aleksandrov A, Hadjiiska R, Iaydjiev P, Rodozov M, Stoykova S, Sultanov G, Vutova M, Dimitrov A, Glushkov I, Litov L, Pavlov B, Petkov P, Fang W, Ahmad M, Bian JG, Chen GM, Chen HS, Chen M, Chen Y, Cheng T, Jiang CH, Leggat D, Liu Z, Romeo F, Ruan M, Shaheen SM, Spiezia A, Tao J, Wang C, Wang Z, Zhang H, Zhao J, Ban Y, Chen G, Li Q, Liu S, Mao Y, Qian SJ, Wang D, Xu Z, Avila C, Cabrera A, Chaparro Sierra LF, Florez C, Gomez JP, González Hernández CF, Ruiz Alvarez JD, Sanabria JC, Godinovic N, Lelas D, Puljak I, Ribeiro Cipriano PM, Sculac T, Antunovic Z, Kovac M, Brigljevic V, Ferencek D, Kadija K, Mesic B, Susa T, Attikis A, Mavromanolakis G, Mousa J, Nicolaou C, Ptochos F, Razis PA, Rykaczewski H, Tsiakkouri D, Finger M, Finger M, Carrera Jarrin E, El-Khateeb E, Elgammal S, Mohamed A, Kadastik M, Perrini L, Raidal M, Tiko A, Veelken C, Eerola P, Pekkanen J, Voutilainen M, Härkönen J, Järvinen T, Karimäki V, Kinnunen R, Lampén T, Lassila-Perini K, Lehti S, Lindén T, Luukka P, Tuominiemi J, Tuovinen E, Wendland L, Talvitie J, Tuuva T, Besancon M, Couderc F, Dejardin M, Denegri D, Fabbro B, Faure JL, Favaro C, Ferri F, Ganjour S, Ghosh S, Givernaud A, Gras P, Hamel de Monchenault G, Jarry P, Kucher I, Locci E, Machet M, Malcles J, Rander J, Rosowsky A, Titov M, Abdulsalam A, Antropov I, Baffioni S, Beaudette F, Busson P, Cadamuro L, Chapon E, Charlot C, Davignon O, Granier de Cassagnac R, Jo M, Lisniak S, Miné P, Nguyen M, Ochando C, Ortona G, Paganini P, Pigard P, Regnard S, Salerno R, Sirois Y, Stahl Leiton AG, Strebler T, Yilmaz Y, Zabi A, Zghiche A, Agram JL, Andrea J, Aubin A, Bloch D, Brom JM, Buttignol M, Chabert EC, Chanon N, Collard C, Conte E, Coubez X, Fontaine JC, Gelé D, Goerlach U, Le Bihan AC, Van Hove P, Gadrat S, Beauceron S, Bernet C, Boudoul G, Carrillo Montoya CA, Chierici R, Contardo D, Courbon B, Depasse P, Mamouni HE, Fay J, Gascon S, Gouzevitch M, Grenier G, Ille B, Lagarde F, Laktineh IB, Lethuillier M, et al.
Eur Phys J C Part Fields
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