Paul B. Yu

Paul Yu, Ph.D., M.D.

Associate Professor of Medicine, Brigham and Women's Hospital
857-307-0390
Publications View
Elafin in pulmonary arterial hypertension. Beyond targeting elastases.
Authors: Authors: Chun HJ, Yu PB.
Am J Respir Crit Care Med
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Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation.
Authors: Authors: Mayeur C, Kolodziej SA, Wang A, Xu X, Lee A, Yu PB, Shen J, Bloch KD, Bloch DB.
Haematologica
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Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency.
Authors: Authors: Malhotra R, Burke MF, Martyn T, Shakartzi HR, Thayer TE, O'Rourke C, Li P, Derwall M, Spagnolli E, Kolodziej SA, Hoeft K, Mayeur C, Jiramongkolchai P, Kumar R, Buys ES, Yu PB, Bloch KD, Bloch DB.
PLoS One
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Specific activin receptor-like kinase 3 inhibitors enhance liver regeneration.
Authors: Authors: Tsugawa D, Oya Y, Masuzaki R, Ray K, Engers DW, Dib M, Do N, Kuramitsu K, Ho K, Frist A, Yu PB, Bloch KD, Lindsley CW, Hopkins CR, Hong CC, Karp SJ.
J Pharmacol Exp Ther
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Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
Authors: Authors: Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB.
J Med Chem
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C-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via Smad dephosphorylation.
Authors: Authors: Zhao Y, Xiao M, Sun B, Zhang Z, Shen T, Duan X, Yu PB, Feng XH, Lin X.
J Biol Chem
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HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression.
Authors: Authors: Wu XG, Wang Y, Wu Q, Cheng WH, Liu W, Zhao Y, Mayeur C, Schmidt PJ, Yu PB, Wang F, Xia Y.
Blood
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The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.
Authors: Authors: Mayeur C, Lohmeyer LK, Leyton P, Kao SM, Pappas AE, Kolodziej SA, Spagnolli E, Yu B, Galdos RL, Yu PB, Peterson RT, Bloch DB, Bloch KD, Steinbicker AU.
Blood
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Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice.
Authors: Authors: Komatsu Y, Yu PB, Kamiya N, Pan H, Fukuda T, Scott GJ, Ray MK, Yamamura K, Mishina Y.
J Bone Miner Res
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Constitutively active ALK2 receptor mutants require type II receptor cooperation.
Authors: Authors: Bagarova J, Vonner AJ, Armstrong KA, Börgermann J, Lai CS, Deng DY, Beppu H, Alfano I, Filippakopoulos P, Morrell NW, Bullock AN, Knaus P, Mishina Y, Yu PB.
Mol Cell Biol
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