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Dominic M. Walsh, Ph.D.

Lecturer on Neurology
617-525-5059
Publications View
Diffusible, highly bioactive oligomers represent a critical minority of soluble Aß in Alzheimer's disease brain.
Authors: Authors: Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DM.
Acta Neuropathol
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Extracellular Forms of Aß and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity.
Authors: Authors: Hu NW, Corbett GT, Moore S, Klyubin I, O'Malley TT, Walsh DM, Livesey FJ, Rowan MJ.
Cell Rep
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Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.
Authors: Authors: Guix FX, Corbett GT, Cha DJ, Mustapic M, Liu W, Mengel D, Chen Z, Aikawa E, Young-Pearse T, Kapogiannis D, Selkoe DJ, Walsh DM.
Int J Mol Sci
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Production and Use of Recombinant Aß for Aggregation Studies.
Authors: Authors: O'Malley TT, Linse S, Walsh DM.
Methods Mol Biol
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Human Brain-Derived Aß Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
Authors: Authors: Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse TL, Spires-Jones TL, Walsh DM.
J Neurosci
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Soluble Aß aggregates can inhibit prion propagation.
Authors: Authors: Sarell CJ, Quarterman E, Yip DC, Terry C, Nicoll AJ, Wadsworth JDF, Farrow MA, Walsh DM, Collinge J.
Open Biol
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Peripheral Interventions Enhancing Brain Glutamate Homeostasis Relieve Amyloid ß- and TNFa- Mediated Synaptic Plasticity Disruption in the Rat Hippocampus.
Authors: Authors: Zhang D, Mably AJ, Walsh DM, Rowan MJ.
Cereb Cortex
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Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.
Authors: Authors: Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A.
Cancer Cell
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Large Soluble Oligomers of Amyloid ß-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
Authors: Authors: Yang T, Li S, Xu H, Walsh DM, Selkoe DJ.
J Neurosci
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The Aggregation Paths and Products of Aß42 Dimers Are Distinct from Those of the Aß42 Monomer.
Authors: Authors: O'Malley TT, Witbold WM, Linse S, Walsh DM.
Biochemistry
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