Dominic M. Walsh

Dominic M. Walsh, Ph.D.

Lecturer on Neurology

617-525-5059

Publications

Publications View

Non-Fibrillar Oligomeric Amyloid-ß within Synapses.

Authors: Authors: Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL.
J Alzheimers Dis 2016-05-30
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A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration.

Authors: Authors: Walsh DM, Selkoe DJ.
Nat Rev Neurosci 2016-04-01
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Soluble Aß oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance.

Authors: Authors: Lei M, Xu H, Li Z, Wang Z, O'Malley TT, Zhang D, Walsh DM, Xu P, Selkoe DJ, Li S.
Neurobiol Dis 2016-01-01
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N-Terminal Extensions Retard Aß42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aß42.

Authors: Authors: Szczepankiewicz O, Linse B, Meisl G, Thulin E, Frohm B, Sala Frigerio C, Colvin MT, Jacavone AC, Griffin RG, Knowles T, Walsh DM, Linse S.
J Am Chem Soc 2015-11-25
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The aqueous phase of Alzheimer's disease brain contains assemblies built from ~4 and ~7 kDa Aß species.

Authors: Authors: Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM, Frosch MP, Walsh DM.
Alzheimers Dement 2015-11-01
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Targeted Magnetic Nanoparticles for Remote Magnetothermal Disruption of Amyloid-ß Aggregates.

Authors: Authors: Loynachan CN, Romero G, Christiansen MG, Chen R, Ellison R, O'Malley TT, Froriep UP, Walsh DM, Anikeeva P.
Adv Healthc Mater 2015-10-01
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Anti-Aß antibodies incapable of reducing cerebral Aß oligomers fail to attenuate spatial reference memory deficits in J20 mice.

Authors: Authors: Mably AJ, Liu W, Mc Donald JM, Dodart JC, Bard F, Lemere CA, O'Nuallain B, Walsh DM.
Neurobiol Dis 2015-10-01
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Real-Time Monitoring of Alzheimer's-Related Amyloid Aggregation via Probe Enhancement-Fluorescence Correlation Spectroscopy.

Authors: Authors: Guan Y, Cao KJ, Cantlon A, Elbel K, Theodorakis EA, Walsh DM, Yang J, Shah JV.
ACS Chem Neurosci 2015-09-16
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Autoregulated paracellular clearance of amyloid-ß across the blood-brain barrier.

Authors: Authors: Keaney J, Walsh DM, O'Malley T, Hudson N, Crosbie DE, Loftus T, Sheehan F, McDaid J, Humphries MM, Callanan JJ, Brett FM, Farrell MA, Humphries P, Campbell M.
Sci Adv 2015-09-04
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Lessons from a Rare Familial Dementia: Amyloid and Beyond.

Authors: Authors: Cantlon A, Frigerio CS, Walsh DM.
J Parkinsons Dis Alzheimers Dis 2015-08-01
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