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Thomas Michel, M.D., Ph.D.

Professor of Medicine
617-732-7376
Publications View
Monitoring methionine sulfoxide with stereospecific mechanism-based fluorescent sensors.
Authors: Authors: Tarrago L, Péterfi Z, Lee BC, Michel T, Gladyshev VN.
Nat Chem Biol
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Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.
Authors: Authors: Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE.
J Biol Chem
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Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium.
Authors: Authors: Kalwa H, Sartoretto JL, Martinelli R, Romero N, Steinhorn BS, Tao M, Ozaki CK, Carman CV, Michel T.
Proc Natl Acad Sci U S A
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Endothelial PGC-1a mediates vascular dysfunction in diabetes.
Authors: Authors: Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, Kang KT, Bischoff J, Kalwa H, Sartoretto JL, Kamei Y, Benjamin LE, Watada H, Ogawa Y, Higashikuni Y, Kessinger CW, Jaffer FA, Michel T, Sata M, Croce K, Tanaka R, Arany Z.
Cell Metab
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Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium.
Authors: Authors: Shiroto T, Romero N, Sugiyama T, Sartoretto JL, Kalwa H, Yan Z, Shimokawa H, Michel T.
PLoS One
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Role of PTEN in modulation of ADP-dependent signaling pathways in vascular endothelial cells.
Authors: Authors: Bretón-Romero R, Kalwa H, Lamas S, Michel T.
Biochim Biophys Acta
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R is for arginine: metabolism of arginine takes off again, in new directions.
Authors: Authors: Michel T.
Circulation
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Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium.
Authors: Authors: Tatematsu S, Francis SA, Natarajan P, Rader DJ, Saghatelian A, Brown JD, Michel T, Plutzky J.
Arterioscler Thromb Vasc Biol
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Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.
Authors: Authors: Ersoy BA, Tarun A, D'Aquino K, Hancer NJ, Ukomadu C, White MF, Michel T, Manning BD, Cohen DE.
Sci Signal
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In vivo imaging of nitric oxide and hydrogen peroxide in cardiac myocytes.
Authors: Authors: Sartoretto JL, Kalwa H, Romero N, Michel T.
Methods Enzymol
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