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Steven E. Shoelson, M.D., Ph.D.

Professor of Medicine
617-732-2528
Publications View
Sustained NF-?B activation and inhibition in ß-cells have minimal effects on function and islet transplant outcomes.
Authors: Authors: King AJ, Guo Y, Cai D, Hollister-Lock J, Morris B, Salvatori A, Corbett JA, Bonner-Weir S, Shoelson SE, Weir GC.
PLoS One
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Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes.
Authors: Authors: Mima A, Qi W, Hiraoka-Yamomoto J, Park K, Matsumoto M, Kitada M, Li Q, Mizutani K, Yu E, Shimada T, Lee J, Shoelson SE, Jobin C, Rask-Madsen C, King GL.
Invest Ophthalmol Vis Sci
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Role of IGF-I and the TNFa/NF-?B pathway in the induction of muscle atrogenes by acute inflammation.
Authors: Authors: Schakman O, Dehoux M, Bouchuari S, Delaere S, Lause P, Decroly N, Shoelson SE, Thissen JP.
Am J Physiol Endocrinol Metab
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NF-?B activation is required for the transition of pulmonary inflammation to muscle atrophy.
Authors: Authors: Langen RC, Haegens A, Vernooy JH, Wouters EF, de Winther MP, Carlsen H, Steele C, Shoelson SE, Schols AM.
Am J Respir Cell Mol Biol
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Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets.
Authors: Authors: Romeo GR, Lee J, Shoelson SE.
Arterioscler Thromb Vasc Biol
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PPAR-? is a major driver of the accumulation and phenotype of adipose tissue Treg cells.
Authors: Authors: Cipolletta D, Feuerer M, Li A, Kamei N, Lee J, Shoelson SE, Benoist C, Mathis D.
Nature
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Hepatocyte-specific IKKß expression aggravates atherosclerosis development in APOE*3-Leiden mice.
Authors: Authors: Wong MC, van Diepen JA, Hu L, Guigas B, de Boer HC, van Puijvelde GH, Kuiper J, van Zonneveld AJ, Shoelson SE, Voshol PJ, Romijn JA, Havekes LM, Tamsma JT, Rensen PC, Hiemstra PS, Berbée JF.
Atherosclerosis
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NF-?B activation and polyubiquitin conjugation are required for pulmonary inflammation-induced diaphragm atrophy.
Authors: Authors: Haegens A, Schols AM, Gorissen SH, van Essen AL, Snepvangers F, Gray DA, Shoelson SE, Langen RC.
Am J Physiol Lung Cell Mol Physiol
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Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet.
Authors: Authors: van Diepen JA, Vroegrijk IO, Berbée JF, Shoelson SE, Romijn JA, Havekes LM, Rensen PC, Voshol PJ.
Am J Physiol Endocrinol Metab
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Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
Authors: Authors: Park SY, Jin W, Woo JR, Shoelson SE.
J Biol Chem
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