Charles Nicholas Serhan

Charles Nicholas Serhan, Ph.D.

Simon Gelman Professor of Anaesthesia
617-525-5001
Publications View
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells.
Authors: Authors: Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA.
FASEB J
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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases.
Authors: Authors: Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, Sukhatme V, Hammock BD, Kieran MW, Huang S, Bhasin M, Serhan CN, Sukhatme VP.
J Clin Invest
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Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome.
Authors: Authors: Werner M, Jordan PM, Romp E, Czapka A, Rao Z, Kretzer C, Koeberle A, Garscha U, Pace S, Claesson HE, Serhan CN, Werz O, Gerstmeier J.
FASEB J
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Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology.
Authors: Authors: Dalli J, Serhan CN.
Br J Pharmacol
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Aspirin-triggered proresolving mediators stimulate resolution in cancer.
Authors: Authors: Gilligan MM, Gartung A, Sulciner ML, Norris PC, Sukhatme VP, Bielenberg DR, Huang S, Kieran MW, Serhan CN, Panigrahy D.
Proc Natl Acad Sci U S A
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Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells.
Authors: Authors: Kaye R, Botten N, Lippestad M, Li D, Hodges RR, Utheim TP, Serhan CN, Dartt DA.
Exp Eye Res
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Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions.
Authors: Authors: Chiang N, Barnaeva E, Hu X, Marugan J, Southall N, Ferrer M, Serhan CN.
Cell Chem Biol
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Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3?DPA.
Authors: Authors: Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN, Kalesse M, Hansen TV.
Chemistry
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Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1.
Authors: Authors: Matte A, Recchiuti A, Federti E, Koehl B, Mintz T, El Nemer W, Tharaux PL, Brousse V, Andolfo I, Lamolinara A, Weinberg O, Siciliano A, Norris PC, Riley IR, Iolascon A, Serhan CN, Brugnara C, De Franceschi L.
Blood
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Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model.
Authors: Authors: Saban DR, Hodges RR, Mathew R, Reyes NJ, Yu C, Kaye R, Swift W, Botten N, Serhan CN, Dartt DA.
Mucosal Immunol
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