ALL | A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Displaying 1 - 4 of 4
Gerhard Wagner
Elkan Blout Professor of Biological Chemistry and Molecular Pharmacology

Our research is concerned with structures of proteins and protein complexes and their functional roles. We use NMR spectroscopy, other biophysical techniques, computational tools and small molecule inhibitors to reveal mechanisms and cellular significance of protein interactions.

Johannes Walter
Professor of Biological Chemistry and Molecular Pharmacology

Vertebrate cells employ intricate mechanisms to duplicate their genomes and guard against DNA damage. Xenopus laevis frog egg extracts have an extraordinary capacity to recapitulate these processes in the test tube, allowing us to elucidate the underlying mechanisms.  Using this system, we study how the replicative DNA helicase unwinds DNA, how it is unloaded from chromatin during replication termination, and how its re-loading is prevented to limit replication to a single round per cell cycle.

Wesley Wong
Assistant Professor of Biological Chemistry and Molecular Pharmacology

We are interested in understanding the physical basis of how biological systems work at the nanoscale, with a focus on the role of mechanical force.

Hao Wu
Asa and Patricia Springer Professor of Structural Biology, Professor of Biological Chemistry and Molecular Pharmacology

The Wu laboratory of “structural immunology” focuses on elucidating the molecular mechanism of signal transduction by immune receptors, especially innate immune receptors.