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Andrew Lassar
Professor of Biological Chemistry and Molecular Pharmacology

Current work in the Lassar Lab focuses on the transcriptional regulatory pathways that regulate chondrocyte formation and maturation, elucidation of how mechanical loading regulates gene expression in the joint, a molecular dissection of the signals and transcription factors that maintain articular cartilage stem cells, and the development of a gene therapy model to treat osteoarthritis.

Joseph Loparo
Associate Professor of Biological Chemistry and Molecular Pharmacology

The Loparo laboratory utilizes single-molecule methods to understand the dynamics of the multiprotein complexes involved in genome maintenance. We aim to develop approaches that allow us to probe the structure and function of these complexes in real time in order to better understand how their assembly and activity are regulated.